Dapk3 | death-associated protein kinase 3

GeneMGI:1203520Synonyms: ZIP kinase

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

64Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Dapk3^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
hyperactivity	2 supporting datasets	Dapk3^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.23x10^-8
preweaning lethality, complete penetrance	1 supporting dataset	Dapk3^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Dapk3^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dapk3.

Associated images

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Histopathology

There is no histopathology data found for Dapk3.

IMPC related publications

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External links

No external links available for Dapk3.

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*Dapk3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dapk3^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dapk3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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