Rhag | Rhesus blood group-associated A glycoprotein

GeneMGI:1202713Synonyms: Rh50, Rh50A, +1 more

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



small testis	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased mean corpuscular hemoglobin	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.81x10^-8
increased circulating total protein level	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.34x10^-5
enlarged lymph nodes	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.65x10^-6
abnormal lymph node morphology	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating cholesterol level	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.69x10^-5
abnormal thymus morphology	1 supporting dataset	Rhag^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rhag.

Associated images

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Histopathology

There is no histopathology data found for Rhag.

IMPC related publications

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External links

No external links available for Rhag.

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*Rhag^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Rhag^{tm1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Rhag^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Rhag^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Rhag^{tm44734(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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