Sec61g | SEC61 translocon subunit gamma
GeneMGI:1202066
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Integument Behavior/neurological Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| tremors | 1 supporting dataset | Sec61gem1(IMPC)J | heterozygote | Early adult | 6.96x10-5 | ||
| preweaning lethality, complete penetrance | 2 supporting datasets | Sec61gem1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Sec61gem1(IMPC)J | heterozygote | Early adult | 3.22x10-5 |
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Human diseases caused by Sec61g mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Sec61g.
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| Sec61gem1(IMPC)J | Whole-gene deletion | | mouse |
| Sec61gtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sec61gtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |