Pde1a | phosphodiesterase 1A, calmodulin-dependent
GeneMGI:1201792
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased blood urea nitrogen level | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Early adult | 9.77x10-6 | ||
| hyperactivity | 2 supporting datasets | Pde1aem1(IMPC)H | homozygote | Early adult | 2.69x10-5 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Early adult | 2.9x10-5 | ||
| decreased total body fat amount | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Late adult | 5.46x10-5 | ||
| increased lean body mass | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Late adult | 5.07x10-5 | ||
| abnormal gait | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Early adult | 8.77x10-6 | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Pde1aem1(IMPC)H | homozygote | Late adult | 2.19x10-6 |
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External links
No external links available for Pde1a.
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| Pde1aem1(IMPC)H | Exon Deletion | | mouse |
| Pde1aem2(IMPC)H | Exon Deletion | | mouse |
| Pde1atm39347(L1L2_gt2) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |