Atp6v1a | ATPase, H+ transporting, lysosomal V1 subunit A

GeneMGI:1201780Synonyms: lysosomal 70kDa, VPP2, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Skeleton Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Atp6v1a^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Atp6v1a^em1(IMPC)Bay	heterozygote	Early adult	2.88x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atp6v1a.

Associated images

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Histopathology

There is no histopathology data found for Atp6v1a.

IMPC related publications

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External links

No external links available for Atp6v1a.

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*Atp6v1a^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Atp6v1a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Atp6v1a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Atp6v1a^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Atp6v1a^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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