Ctbp2 | C-terminal binding protein 2

GeneMGI:1201686Synonyms: Gtrgeo6, D7Ertd45e, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Behavior/neurological Mortality/aging Cardiovascular system

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Ctbp2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal somite shape	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal pericardium morphology	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal heart morphology	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
edema	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
decreased exploration in new environment	1 supporting dataset	Ctbp2^em1(IMPC)Bay	heterozygote	Early adult	5.54x10^-5
prenatal lethality prior to heart atrial septation	1 supporting dataset	Ctbp2^em1(IMPC)Bay	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ctbp2.

Associated images

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Histopathology

There is no histopathology data found for Ctbp2.

IMPC related publications

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External links

No external links available for Ctbp2.

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*Ctbp2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Ctbp2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ctbp2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ctbp2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Ctbp2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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