Shox2 | SHOX homeobox 2

GeneMGI:1201673Synonyms: 6330543G17Rik, Prx3, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Mortality/aging Cardiovascular system

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal retina blood vessel morphology	1 supporting dataset	Shox2^em1(IMPC)Bay	heterozygote	Early adult	7.62x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Shox2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Shox2^em1(IMPC)Bay	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Shox2.

Associated images

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Histopathology

There is no histopathology data found for Shox2.

IMPC related publications

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External links

No external links available for Shox2.

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*Shox2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Shox2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Shox2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes