Cer1 | cerberus 1, DAN family BMP antagonist

GeneMGI:1201414Synonyms: cer-1, Cerl, +3 more

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Cardiovascular system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



vertebral transformation	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.02x10^-6
abnormal thymus morphology	2 supporting datasets	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.8x10^-5
abnormal heart morphology	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal vertebrae morphology	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.21x10^-9
enlarged heart	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal vertebral arch morphology	2 supporting datasets	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.62x10^-5
abnormal testis morphology	1 supporting dataset	Cer1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cer1.

Associated images

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Histopathology

There is no histopathology data found for Cer1.

IMPC related publications

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External links

No external links available for Cer1.

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*Cer1^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Cer1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Cer1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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