Sh2b1 | SH2B adaptor protein 1

GeneMGI:1201407Synonyms: SH2-B, Sh2bpsm1, +2 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



impaired glucose tolerance	1 supporting dataset		Sh2b1^em1(IMPC)Ics	heterozygote	Early adult		2.5x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sh2b1.

Associated images

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Histopathology

There is no histopathology data found for Sh2b1.

IMPC related publications

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External links

No external links available for Sh2b1.

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*Sh2b1^em1(IMPC)Ics*	Deletion	‌	mouse
*Sh2b1^{tm380622(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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