Bcl2l11 | BCL2 like 11

GeneMGI:1197519Synonyms: Bim, Bod, +1 more

Physiological systems

15 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

9 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult4.93x10-5 
increased leukocyte cell number1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult1.95x10-8 
increased grip strength2 supporting datasetsBcl2l11em1(IMPC)HhomozygoteEarly adult7.96x10-5 
increased circulating potassium level1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult6.07x10-6 
decreased total body fat amount1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult5.9x10-5 
increased lymphocyte cell number1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult1.38x10-7 
increased erythrocyte cell number1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult9.03x10-6 
increased spleen weight1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult8.25x10-6 
increased large unstained cell number1 supporting datasetBcl2l11em1(IMPC)HhomozygoteEarly adult5.22x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bcl2l11em1(IMPC)HIndelmouse
Bcl2l11em2(IMPC)HIndelmouse
Bcl2l11tm281630(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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