Pole2 | polymerase (DNA directed), epsilon 2 (p59 subunit)
Physiological systems
22 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Embryo Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Cardiovascular system Mortality/aging
9 No significant impact
2 Not tested
Data collections
Gene metrics:19Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Pole2 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pole2.