Sumo1 | small ubiquitin-like modifier 1

GeneMGI:1197010Synonyms: SENTRIN, Ubl1, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Respiratory system Cardiovascular system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged heart	1 supporting dataset	Sumo1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Sumo1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal lung morphology	1 supporting dataset	Sumo1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
preweaning lethality, incomplete penetrance	1 supporting dataset	Sumo1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sumo1.

Associated images

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Histopathology

There is no histopathology data found for Sumo1.

IMPC related publications

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External links

No external links available for Sumo1.

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*Sumo1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Sumo1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Sumo1^{tm114751(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Sumo1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sumo1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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