Ctdspl2 | CTD small phosphatase like 2

GeneMGI:1196405Synonyms: D2Ertd485e, SCP4

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	2 supporting datasets	Ctdspl2^{tm2b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Ctdspl2^{tm2b(KOMP)Wtsi}	heterozygote	E18.5	N/A ^*
increased spleen weight	1 supporting dataset	Ctdspl2^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	4.4x10^-6
decreased total body fat amount	1 supporting dataset	Ctdspl2^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	3.45x10^-6
increased lean body mass	1 supporting dataset	Ctdspl2^{tm2b(KOMP)Wtsi}	heterozygote	Early adult	1x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ctdspl2.

Associated images

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Histopathology

There is no histopathology data found for Ctdspl2.

IMPC related publications

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External links

No external links available for Ctdspl2.

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*Ctdspl2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ctdspl2^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ctdspl2^{tm2b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ctdspl2^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ctdspl2^{tm35033(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ctdspl2^{tm356669(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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