D16Ertd472e | DNA segment, Chr 16, ERATO Doi 472, expressed
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Hematopoietic system Behavior/neurological
16 No significant impact
5 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total retina thickness | 1 supporting dataset | D16Ertd472etm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.11x10-7 | ||
| decreased mean corpuscular volume | 1 supporting dataset | D16Ertd472etm1b(EUCOMM)Wtsi | homozygote | Early adult | 4.78x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | D16Ertd472etm1b(EUCOMM)Wtsi | homozygote | Early adult | 7.5x10-6 |
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Human diseases caused by D16Ertd472e mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for D16Ertd472e.
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| D16Ertd472etm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| D16Ertd472etm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| D16Ertd472etm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |