Ptpn20 | protein tyrosine phosphatase, non-receptor type 20

GeneMGI:1196295Synonyms: typ

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Phy. System:



increased circulating chloride level	1 supporting dataset	Ptpn20^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.65x10^-5
limb grasping	1 supporting dataset	Ptpn20^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.33x10^-8
abnormal lens morphology	1 supporting dataset	Ptpn20^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.98x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ptpn20.

Associated images

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Histopathology

There is no histopathology data found for Ptpn20.

IMPC related publications

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External links

No external links available for Ptpn20.

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*Ptpn20^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ptpn20^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes