Cdca8 | cell division cycle associated 8

GeneMGI:1196274Synonyms: Borealin, D4Ertd421e, +2 more

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating chloride level1 supporting datasetCdca8tm1a(KOMP)WtsiheterozygoteEarly adult4.73x10-6 
increased circulating LDL cholesterol level1 supporting datasetCdca8tm1a(KOMP)WtsiheterozygoteEarly adult4.3x10-5 
increased circulating alkaline phosphatase level1 supporting datasetCdca8tm1a(KOMP)WtsiheterozygoteEarly adult6.25x10-5 
increased thermal nociceptive threshold1 supporting datasetCdca8tm1a(KOMP)WtsiheterozygoteEarly adult6.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdca8tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cdca8tm356569(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cdca8tm36738(pL1L2_GT1_DelLacZ_bsd)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cdca8tm36738(pL1L2_frt_BetactP_neo_frt_lox)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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