Klrk1 | killer cell lectin-like receptor subfamily K, member 1

GeneMGI:1196250Synonyms: NKG2-D, D6H12S2489E, +1 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Hematopoietic system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsKlrk1em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetKlrk1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetKlrk1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klrk1em1(IMPC)MbpInter-exon deletionmouse
Klrk1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Klrk1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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