Septin5 | septin 5
Physiological systems
17 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging
10 No significant impact
7 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:76Adult tissues
50Embryo tissues
| decreased body length | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.7x10-5 | ||
| short tibia | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.68x10-6 | ||
| improved glucose tolerance | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.74x10-5 | ||
| thrombocytopenia | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.79x10-10 | ||
| small spleen | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | N/A * | ||
| abnormal bone structure | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.8x10-5 | ||
| decreased bone mineral density | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.75x10-5 | ||
| decreased bone mineral content | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.58x10-6 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Septin5tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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| adrenal gland | heterozygote | Wholemount images | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | Wholemount images | 100% (4/4) | 0.19% (1/533) |
| bone | heterozygote | Wholemount images | 100% (4/4) | 0% (0/394) |
| brain | heterozygote | Wholemount images | 100% (4/4) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 100% (4/4) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/4) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 100% (4/4) | 0.22% (1/454) |
| cecum | heterozygote | Wholemount images | 100% (4/4) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 100% (4/4) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 100% (4/4) | 0.41% (2/491) |
External links
No external links available for Septin5.
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| Septin5tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Septin5tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |