Per2 | period circadian clock 2

GeneMGI:1195265Synonyms: mPer2

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Integument Growth/size/body region Behavior/neurological Skeleton

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral density	1 supporting dataset	Per2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	8.2x10^-5
abnormal behavior	1 supporting dataset	Per2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.94x10^-5
increased lean body mass	1 supporting dataset	Per2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.02x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Per2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.51x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Per2^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.34x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Per2.

Associated images

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Histopathology

There is no histopathology data found for Per2.

IMPC related publications

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External links

No external links available for Per2.

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*Per2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Per2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Per2^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse
*Per2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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