Ppl | periplakin

GeneMGI:1194898

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Integument Behavior/neurological Renal/urinary system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:42Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal skin morphology	1 supporting dataset	Ppl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Ppl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Ppl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.93x10^-8
small kidney	1 supporting dataset	Ppl^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppl.

Associated images

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Histopathology

There is no histopathology data found for Ppl.

IMPC related publications

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External links

No external links available for Ppl.

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*Ppl^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ppl^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ppl^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes