Ddost | dolichyl-di-phosphooligosaccharide-protein glycotransferase
GeneMGI:1194508
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Hematopoietic system Mortality/aging
16 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:43Adult tissues
30Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Ddosttm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| small adrenal glands | 1 supporting dataset | Ddosttm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Ddosttm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Ddosttm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| decreased hemoglobin content | 1 supporting dataset | Ddosttm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.17x10-6 | ||
| enlarged lymph nodes | 2 supporting datasets | Ddosttm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| small spleen | 1 supporting dataset | Ddosttm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
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| Ddosttm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Ddosttm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ddosttm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |