H3f3b | H3.3 histone B

GeneMGI:1101768Synonyms: H3.3B, H3-3b, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Renal/urinary system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal kidney morphology	1 supporting dataset	H3f3b^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased circulating cholesterol level	1 supporting dataset	H3f3b^{tm1.1(KOMP)Mbp}	homozygote	Early adult	9.11x10^-7
increased startle reflex	1 supporting dataset	H3f3b^{tm1.1(KOMP)Mbp}	homozygote	Early adult	2.35x10^-6
polycystic kidney	1 supporting dataset	H3f3b^{tm1.1(KOMP)Mbp}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for H3f3b.

Associated images

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Histopathology

There is no histopathology data found for H3f3b.

IMPC related publications

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External links

No external links available for H3f3b.

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*H3f3b^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*H3f3b^{tm1.1(KOMP)Mbp}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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