Mras | muscle and microspikes RAS

GeneMGI:1100856Synonyms: 2900078C09Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Mras^em1(IMPC)H	homozygote	Early adult	2x10^-5
increased circulating creatinine level	1 supporting dataset	Mras^em1(IMPC)H	homozygote	Early adult	7.96x10^-5
decreased locomotor activity	4 supporting datasets	Mras^em1(IMPC)H	homozygote	Early adult	1.92x10^-6
increased thigmotaxis	2 supporting datasets	Mras^em1(IMPC)H	homozygote	Early adult	6.95x10^-5
decreased total body fat amount	2 supporting datasets	Mras^em1(IMPC)H	homozygote	Early adult	8.77x10^-6
abnormal behavior	1 supporting dataset	Mras^em1(IMPC)H	homozygote	Early adult	6.95x10^-5
increased anxiety-related response	1 supporting dataset	Mras^em1(IMPC)H	homozygote	Early adult	1.98x10^-5
decreased exploration in new environment	1 supporting dataset	Mras^em1(IMPC)H	homozygote	Early adult	8.78x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mras.

Associated images

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Histopathology

There is no histopathology data found for Mras.

IMPC related publications

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External links

No external links available for Mras.

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*Mras^em1(IMPC)H*	Inter-exon deletion	‌	mouse
*Mras^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Mras^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Mras^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Mras^{tm47682(L1L2_gt1_Del_LacZ)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Mras^{tm47682(pL1L2_frt15_BetactinBSD_frt14_neo_Rox)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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