Mid1 | midline 1

GeneMGI:1100537Synonyms: Fxy, 61B3-R, +2 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Adipose tissue Growth/size/body region Nervous system Vision/eye Behavior/neurological Cardiovascular system Renal/urinary system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small kidney1 supporting datasetMid1em1(IMPC)MbpheterozygoteEarly adultN/A * 
increased freezing behavior1 supporting datasetMid1em1(IMPC)MbpheterozygoteEarly adult2.74x10-5 
enlarged kidney1 supporting datasetMid1em1(IMPC)MbphemizygoteEarly adultN/A * 
increased lean body mass1 supporting datasetMid1em1(IMPC)MbpheterozygoteEarly adult3.26x10-5 
single kidney1 supporting datasetMid1em1(IMPC)MbphemizygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetMid1em1(IMPC)MbpheterozygoteEarly adult3.63x10-5 
persistence of hyaloid vascular system1 supporting datasetMid1em1(IMPC)MbphemizygoteEarly adult1.31x10-5 
increased heart weight2 supporting datasetsMid1em1(IMPC)MbpheterozygoteEarly adult3.6x10-6 
abnormal kidney morphology1 supporting datasetMid1em1(IMPC)MbphemizygoteEarly adultN/A * 
decreased total body fat amount1 supporting datasetMid1em1(IMPC)MbpheterozygoteEarly adult1.84x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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