Nnmt | nicotinamide N-methyltransferase
GeneMGI:1099443
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system
14 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged ovary | 1 supporting dataset | Nnmtem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal pancreas morphology | 1 supporting dataset | Nnmtem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal skin morphology | 1 supporting dataset | Nnmtem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| abnormal ovary morphology | 1 supporting dataset | Nnmtem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Nnmtem1(IMPC)Mbp | homozygote | Late adult | N/A * |
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Human diseases caused by Nnmt mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nnmt.
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| Nnmtem1(IMPC)Mbp | Exon Deletion | | mouse |
| Nnmttm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |