Nnmt | nicotinamide N-methyltransferase

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system

14 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged ovary1 supporting datasetNnmtem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal pancreas morphology1 supporting datasetNnmtem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetNnmtem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetNnmtem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen1 supporting datasetNnmtem1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nnmtem1(IMPC)MbpExon Deletionmouse
Nnmttm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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