Sptlc1 | serine palmitoyltransferase, long chain base subunit 1

GeneMGI:1099431Synonyms: Spt1, Lcb1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Embryo Growth/size/body region Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Sptlc1^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Sptlc1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Sptlc1^em1(IMPC)Bay	heterozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sptlc1.

Associated images

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Histopathology

There is no histopathology data found for Sptlc1.

IMPC related publications

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External links

No external links available for Sptlc1.

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*Sptlc1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Sptlc1^{tm380302(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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