Sepsecs | Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Hematopoietic system Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| embryonic lethality prior to organogenesis | 1 supporting dataset | Sepsecsem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Sepsecsem1(IMPC)Tcp | heterozygote | Early adult | 9.77x10-6 | ||
| thick skin | 1 supporting dataset | Sepsecsem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Sepsecsem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Sepsecsem1(IMPC)Tcp | heterozygote | Early adult | 2.56x10-6 | ||
| increased circulating calcium level | 1 supporting dataset | Sepsecsem1(IMPC)Tcp | heterozygote | Early adult | 5.65x10-5 |
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External links
No external links available for Sepsecs.
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| Sepsecsem1(IMPC)Tcp | Exon Deletion | | mouse |
| Sepsecstm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Sepsecstm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |