Trappc1 | trafficking protein particle complex 1

GeneMGI:1098727Synonyms: D11Ertd172e, BET5, +1 more

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Liver/biliary system Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

12 No significant impact

2 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsTrappc1em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney2 supporting datasetsTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetTrappc1em1(IMPC)MbphomozygoteE15.5N/A * 
small testis1 supporting datasetTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
small heart1 supporting datasetTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal testis morphology1 supporting datasetTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged heart1 supporting datasetTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
enlarged spleen2 supporting datasetsTrappc1em1(IMPC)MbpheterozygoteLate adultN/A * 
embryonic lethality prior to organogenesis1 supporting datasetTrappc1em1(IMPC)MbphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trappc1em1(IMPC)MbpExon Deletionmouse
Trappc1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Trappc1tm446276(L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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