Tmem38b | transmembrane protein 38B

GeneMGI:1098718Synonyms: D4Ertd89e, 1600017F22Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Embryo Growth/size/body region Vision/eye Mortality/aging Cardiovascular system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal blood vessel morphology1 supporting datasetTmem38bem1(IMPC)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetTmem38bem1(IMPC)MbpheterozygoteE15.5N/A * 
microphthalmia1 supporting datasetTmem38bem1(IMPC)MbphomozygoteE15.5N/A * 
abnormal placenta morphology1 supporting datasetTmem38bem1(IMPC)MbphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsTmem38bem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal placenta morphology1 supporting datasetTmem38bem1(IMPC)MbpheterozygoteE15.5N/A * 
abnormal placenta vasculature1 supporting datasetTmem38bem1(IMPC)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetTmem38bem1(IMPC)MbphomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem38bem1(IMPC)MbpExon Deletionmouse
Tmem38btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Tmem38btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Tmem38btm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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