Parp8 | poly (ADP-ribose) polymerase family, member 8

GeneMGI:1098713Synonyms: D13Ertd275e, 2810430O08Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Behavior/neurological Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

25Embryo tissues

Phenotypes

Phy. System:



decreased exploration in new environment	1 supporting dataset	Parp8^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	1.36x10^-6
increased heart weight	1 supporting dataset	Parp8^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	5.23x10^-5
decreased coping response	1 supporting dataset	Parp8^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	4.07x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Parp8.

Associated images

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Histopathology

There is no histopathology data found for Parp8.

IMPC related publications

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External links

No external links available for Parp8.

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*Parp8^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Parp8^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes