Esyt3 | extended synaptotagmin-like protein 3

GeneMGI:1098699Synonyms: D9Ertd280e, Fam62c

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Esyt3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.59x10^-13
increased mean corpuscular volume	1 supporting dataset	Esyt3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.36x10^-6
decreased erythrocyte cell number	1 supporting dataset	Esyt3^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	5.25x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Esyt3.

Associated images

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Histopathology

There is no histopathology data found for Esyt3.

IMPC related publications

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External links

No external links available for Esyt3.

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*Esyt3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Esyt3^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Esyt3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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