Ift81 | intraflagellar transport 81

GeneMGI:1098597Synonyms: CDV-1R, Cdv1

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.45x10^-7
decreased heart rate	2 supporting datasets	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.79x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.58x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.14x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased grip strength	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.56x10^-6
abnormal retina blood vessel morphology	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.72x10^-6
decreased locomotor activity	2 supporting datasets	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.61x10^-6
abnormal retina morphology	1 supporting dataset	Ift81^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.72x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ift81.

Associated images

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Histopathology

There is no histopathology data found for Ift81.

IMPC related publications

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External links

No external links available for Ift81.

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*Ift81^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ift81^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ift81^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ift81^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ift81^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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