C9 | complement component 9

GeneMGI:1098282

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Phy. System:



increased circulating sodium level	1 supporting dataset	C9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.36x10^-8
increased heart weight	1 supporting dataset	C9^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.01x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for C9.

Associated images

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Histopathology

There is no histopathology data found for C9.

IMPC related publications

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External links

No external links available for C9.

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*C9^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*C9^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*C9^{tm44785(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes