Gse1 | genetic suppressor element 1, coiled-coil protein

GeneMGI:1098275

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Gse1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.8x10^-6
increased circulating alkaline phosphatase level	1 supporting dataset	Gse1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.03x10^-6
decreased erythrocyte cell number	1 supporting dataset	Gse1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.05x10^-5
increased circulating total protein level	1 supporting dataset	Gse1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.32x10^-5
increased heart weight	1 supporting dataset	Gse1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.71x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gse1.

Associated images

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Histopathology

There is no histopathology data found for Gse1.

IMPC related publications

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External links

No external links available for Gse1.

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*Gse1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Gse1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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