Rgs2 | regulator of G-protein signaling 2
Physiological systems
19 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Craniofacial Cardiovascular system
10 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| prolonged PR interval | 1 supporting dataset | Rgs2em1(IMPC)H | heterozygote | Early adult | 5.21x10-5 | ||
| abnormal tooth morphology | 2 supporting datasets | Rgs2em1(IMPC)H | homozygote | Early adult | 9.67x10-7 | ||
| cornea opacity | 1 supporting dataset | Rgs2em1(IMPC)H | homozygote | Late adult | 7.68x10-5 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Rgs2em1(IMPC)H | homozygote | Early adult | 8.51x10-6 | ||
| enlarged spleen | 1 supporting dataset | Rgs2em1(IMPC)H | homozygote | Late adult | N/A * | ||
| increased freezing behavior | 1 supporting dataset | Rgs2em1(IMPC)H | homozygote | Late adult | 2.15x10-8 | ||
| increased circulating creatinine level | 1 supporting dataset | Rgs2em1(IMPC)H | homozygote | Late adult | 8.89x10-9 | ||
| increased large unstained cell number | 1 supporting dataset | Rgs2em1(IMPC)H | heterozygote | Early adult | 6.95x10-5 |
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External links
No external links available for Rgs2.
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| Rgs2em1(IMPC)H | Exon Deletion | | mouse |
| Rgs2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Rgs2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Rgs2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |