Bnc1 | basonuclin zinc finger protein 1

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Pigmentation Endocrine/exocrine gland Integument Hematopoietic system Skeleton

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



small testis	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Bnc1^em1(IMPC)H	homozygote	Late adult	N/A ^*
increased leukocyte cell number	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	4.49x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	1.89x10^-16
abnormal seminal vesicle morphology	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	4.87x10^-5
increased neutrophil cell number	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	2.11x10^-6
increased bone mineral content	2 supporting datasets	Bnc1^em1(IMPC)H	homozygote	Early adult	2.24x10^-5
increased lymphocyte cell number	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Late adult	6.96x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Bnc1^em1(IMPC)H	homozygote	Early adult	4x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bnc1.

Associated images

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Histopathology

There is no histopathology data found for Bnc1.

IMPC related publications

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External links

No external links available for Bnc1.

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*Bnc1^em1(IMPC)H*	Exon Deletion	‌	mouse
*Bnc1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bnc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Bnc1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bnc1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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