Defb1 | defensin beta 1

GeneMGI:1096878Synonyms: mBD-1

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased thigmotaxis	2 supporting datasets	Defb1^em1(IMPC)Mbp	homozygote	Early adult	1.85x10^-16
decreased anxiety-related response	1 supporting dataset	Defb1^em1(IMPC)Mbp	homozygote	Early adult	9.45x10^-13
hyperactivity	2 supporting datasets	Defb1^em1(IMPC)Mbp	homozygote	Early adult	2.3x10^-6
decreased locomotor activity	1 supporting dataset	Defb1^em1(IMPC)Mbp	homozygote	Early adult	1.22x10^-9
abnormal behavior	1 supporting dataset	Defb1^em1(IMPC)Mbp	homozygote	Early adult	2.27x10^-16

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Defb1.

Associated images

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Histopathology

There is no histopathology data found for Defb1.

IMPC related publications

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External links

No external links available for Defb1.

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*Defb1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Defb1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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