Wdfy3 | WD repeat and FYVE domain containing 3

GeneMGI:1096875Synonyms: 2610509D04Rik, Ggtb3, +4 more

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Embryo Growth/size/body region Digestive/alimentary Liver/biliary system Hematopoietic system Craniofacial Mortality/aging Cardiovascular system Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal liver morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Wdfy3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small kidney	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
enlarged spleen	2 supporting datasets	Wdfy3^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
abnormal facial morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal kidney morphology	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	heterozygote	Late adult	N/A ^*
cleft palate	1 supporting dataset	Wdfy3^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wdfy3.

Associated images

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Histopathology

There is no histopathology data found for Wdfy3.

IMPC related publications

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External links

No external links available for Wdfy3.

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*Wdfy3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Wdfy3^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Wdfy3^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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