Utp4 | UTP4 small subunit processome component
Physiological systems
18 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Embryo Nervous system Hematopoietic system Behavior/neurological Mortality/aging
10 No significant impact
6 Not tested
Data collections
Gene metrics:9Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal coat/ hair morphology | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Late adult | 2.62x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Utp4em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| limb grasping | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Late adult | 6.81x10-8 | ||
| abnormal neural tube closure | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | E9.5 | N/A * | ||
| impaired righting response | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Late adult | 2.36x10-7 | ||
| increased leukocyte cell number | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Late adult | 1.59x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Utp4em1(IMPC)J | homozygote | Early adult | N/A * | ||
| absent vibrissae | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Late adult | 1.32x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Utp4em1(IMPC)J | heterozygote | Early adult | 4.04x10-9 |
| | | | | | | | | | |
External links
No external links available for Utp4.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Utp4em1(IMPC)J | Exon Deletion | | mouse |
| Utp4tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Utp4tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |