Snai2 | snail family zinc finger 2

GeneMGI:1096393Synonyms: Slugh, Slug, +1 more

Physiological systems

23 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Pigmentation Integument Embryo Growth/size/body region Nervous system Mortality/aging Cardiovascular system

16 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

47Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	3 supporting datasets	Snai2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
hemorrhage	1 supporting dataset	Snai2^{tm1.1(KOMP)Vlcg}	heterozygote	E15.5	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Snai2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.11x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Snai2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.56x10^-7
spina bifida	1 supporting dataset	Snai2^{tm1.1(KOMP)Vlcg}	heterozygote	E15.5	N/A ^*
enlarged heart	1 supporting dataset	Snai2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snai2.

Associated images

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Histopathology

There is no histopathology data found for Snai2.

IMPC related publications

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External links

No external links available for Snai2.

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*Snai2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Snai2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Snai2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Snai2^{tm295068(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Snai2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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