Erf | Ets2 repressor factor
GeneMGI:109637
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Embryo Growth/size/body region Skeleton Mortality/aging Craniofacial Renal/urinary system
14 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Erftm1.1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Erftm1.1(KOMP)Mbp | heterozygote | E9.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Erftm1.1(KOMP)Mbp | heterozygote | E9.5 | N/A * | ||
| abnormal tooth morphology | 1 supporting dataset | Erftm1.1(KOMP)Mbp | heterozygote | Early adult | 4.79x10-5 | ||
| abnormal snout morphology | 1 supporting dataset | Erftm1.1(KOMP)Mbp | heterozygote | Early adult | 2.75x10-12 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Erftm1.1(KOMP)Mbp | homozygote | E12.5 | N/A * | ||
| urinary bladder obstruction | 1 supporting dataset | Erftm1.1(KOMP)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Erf.
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| Erftm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Erftm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |