Gckr | glucokinase regulatory protein

GeneMGI:1096345Synonyms: GKRP

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



impaired glucose tolerance	1 supporting dataset	Gckr^em1(IMPC)H	homozygote	Early adult	4.81x10^-5
increased circulating creatinine level	1 supporting dataset	Gckr^em1(IMPC)H	homozygote	Early adult	1.15x10^-11
increased blood urea nitrogen level	1 supporting dataset	Gckr^em1(IMPC)H	homozygote	Early adult	1.67x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gckr.

Associated images

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Histopathology

There is no histopathology data found for Gckr.

IMPC related publications

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External links

No external links available for Gckr.

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*Gckr^em1(IMPC)H*	Exon Deletion	‌	mouse
*Gckr^em2(IMPC)H*	Exon Deletion	‌	mouse
*Gckr^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Gckr^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Gckr^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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