Gckr | glucokinase regulatory protein

GeneMGI:1096345Synonyms: GKRP

Physiological systems

16 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

15 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

impaired glucose tolerance1 supporting datasetGckrem1(IMPC)HhomozygoteEarly adult4.81x10-5 
increased circulating creatinine level1 supporting datasetGckrem1(IMPC)HhomozygoteEarly adult1.15x10-11 
increased blood urea nitrogen level1 supporting datasetGckrem1(IMPC)HhomozygoteEarly adult1.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gckrem1(IMPC)HExon Deletionmouse
Gckrem2(IMPC)HExon Deletionmouse
Gckrtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gckrtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gckrtm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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