Lst1 | leukocyte specific transcript 1

GeneMGI:1096324Synonyms: B144

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Adipose tissue Growth/size/body region Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal heart morphology	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.79x10^-5
increased circulating triglyceride level	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	8.94x10^-7
abnormal testis morphology	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
decreased total body fat amount	1 supporting dataset	Lst1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.35x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lst1.

Associated images

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Histopathology

There is no histopathology data found for Lst1.

IMPC related publications

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External links

No external links available for Lst1.

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*Lst1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Lst1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

My Genes