Kmt2b | lysine (K)-specific methyltransferase 2B

GeneMGI:109565Synonyms: 2610014H22Rik, Wbp7, +1 more

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Hematopoietic system

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation2 supporting datasetsKmt2btm1.2(IMPC)WtsiheterozygoteEarly adult3.48x10-5 
increased circulating alkaline phosphatase level1 supporting datasetKmt2btm1.2(IMPC)WtsiheterozygoteEarly adult4.66x10-5 
increased mean corpuscular hemoglobin1 supporting datasetKmt2btm1.2(IMPC)WtsiheterozygoteEarly adult4.43x10-10 
decreased erythrocyte cell number1 supporting datasetKmt2btm1.2(IMPC)WtsiheterozygoteEarly adult7.57x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kmt2btm1(IMPC)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Kmt2btm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Kmt2btm1.2(IMPC)WtsiReporter-tagged deletion allele (post Flp, with no reporter and selection cassette)mouse

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