Kif5a | kinesin family member 5A

GeneMGI:109564Synonyms: Kns, Kif5, +2 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

5Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



cyanosis	1 supporting dataset	Kif5a^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
unresponsive to tactile stimuli	1 supporting dataset	Kif5a^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Kif5a^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
impaired pupillary reflex	1 supporting dataset	Kif5a^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.28x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Kif5a.

Associated images

Loading...

Histopathology

There is no histopathology data found for Kif5a.

IMPC related publications

Loading...

External links

No external links available for Kif5a.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Kif5a^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Kif5a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Kif5a^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Kif5a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes