Slc2a2 | solute carrier family 2 (facilitated glucose transporter), member 2

GeneMGI:1095438Synonyms: Glut-2, liver-type glucose transporter, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

14 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
3Associated diseases
Expression examined in:76Adult tissues
25Embryo tissues

Phenotypes

increased glycosylated hemoglobin level1 supporting datasetSlc2a2tm1b(KOMP)WtsiheterozygoteEarly adult1.12x10-5 
preweaning lethality, complete penetrance1 supporting datasetSlc2a2tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
increased fasting circulating glucose level1 supporting datasetSlc2a2tm1b(KOMP)WtsiheterozygoteEarly adult9.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc2a2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc2a2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc2a2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Slc2a2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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