Dpf2 | double PHD fingers 2

GeneMGI:109529Synonyms: ubi-d4, Req, +3 more

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Integument Embryo Growth/size/body region Limbs/digits/tail Mortality/aging Craniofacial Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

51Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal limb morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	N/A ^*
edema	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal tail morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal kidney morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	N/A ^*
pallor	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal embryo size	1 supporting dataset	Dpf2^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dpf2.

Associated images

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Histopathology

There is no histopathology data found for Dpf2.

IMPC related publications

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External links

No external links available for Dpf2.

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*Dpf2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dpf2^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dpf2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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