Cacna1a | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

GeneMGI:109482Synonyms: SCA6, Cacnl1a4, +4 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
11Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased freezing behavior1 supporting datasetCacna1aem1(IMPC)HheterozygoteEarly adult6.34x10-6 
preweaning lethality, incomplete penetrance1 supporting datasetCacna1aem1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cacna1aem1(IMPC)HExon Deletionmouse
Cacna1atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cacna1atm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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