Atf3 | activating transcription factor 3

GeneMGI:109384Synonyms: LRG-21

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal retina morphology	1 supporting dataset	Atf3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	9.45x10^-6
decreased locomotor activity	1 supporting dataset	Atf3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	9.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atf3.

Associated images

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Histopathology

There is no histopathology data found for Atf3.

IMPC related publications

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External links

No external links available for Atf3.

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*Atf3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Atf3^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Atf3^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Atf3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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