Stx1a | syntaxin 1A (brain)

GeneMGI:109355Synonyms: HPC-1

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness1 supporting datasetStx1atm1b(EUCOMM)HmguhomozygoteEarly adult8.64x10-5 
decreased grip strength1 supporting datasetStx1atm1b(EUCOMM)HmguhomozygoteEarly adult3.72x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Stx1atm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Stx1atm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Stx1atm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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